Autophagy protects against neural cell death induced by piperidine alkaloids present in Prosopis juliflora (Mesquite)
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چکیده
منابع مشابه
The human allergens of mesquite (Prosopis juliflora)
BACKGROUND: A computerized statistical analysis of allergy skin test results correlating patient reactivities initiated our interest in the cross-reactive allergens of mesquite tree pollen. In-vitro testing with mesquite-sensitized rabbits and a variety of deciduous tree pollens revealed so many cross-reactivities that it became apparent there could be more allergens in mesquite than previously...
متن کاملBiology and Impacts of Pacific Island Invasive Species. 6. Prosopis pallida and Prosopis juliflora (Algarroba, Mesquite, Kiawe) (Fabaceae)
Prosopis pallida and P. juliflora (commonly referred to as algarroba, mesquite, or kiawe) were introduced from South America to areas in Oceania, Asia, and Africa during the early nineteenth century. In many cases, they naturalized and became widespread. In some places, alien Prosopis species are highly valued for the products and services that they can provide such as shade, cattle fodder, woo...
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Tumor hypoxia is a common characteristic of most solid tumors and is correlated with poor prognosis for patients partly because hypoxia promotes resistance to cancer therapy. Hypoxia selects cancer cells that are resistant to apoptosis and allows the onset of mechanisms that promote cancer cells survival including autophagy. Previously, we showed that human hepatoma HepG2 cells were protected u...
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Oxaliplatin is included in a number of effective combination regimens used as first and subsequent lines of therapy for metastatic colorectal cancer. Accumulating evidence indicates that autophagy plays a significant role in response to cancer therapy. However, the role of autophagy in oxaliplatin-induced cell death remains to be clarified. In this study, we showed that oxaliplatin induced cell...
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Ecstasy (3,4-methylenedioxymethamphetamine; MDMA) has potent CNS stimulant effects. Besides the acute effects of MDMA, such as psychomotor activation, euphoria, decreased appetite, and hyperthermia, long-term damage of dopaminergic and serotonergic nerve terminals in multiple brain areas have also been reported. Although some studies have demonstrated that considerable amounts of MDMA reach the...
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ژورنال
عنوان ژورنال: Anais da Academia Brasileira de Ciências
سال: 2017
ISSN: 0001-3765
DOI: 10.1590/0001-3765201720160477